Douglas A. Fein received a B.A. degree (magna cum laude) in history from Brown University in 1983 and received an M.D. degree from Bowman Gray School of Medicine in 1989. Dr. Fein completed his residency in radiation oncology at the University of Florida College of Medicine from 1990-1993 where he was elected chief resident in 1992.

Dr. Fein became an associate member of the Department of Radiation Oncology at the Fox Chase Cancer Center in Philadelphia in 1993 where he was appointed director of the residency training program in 1996. In 1997, he joined Texas Oncology, P.A. as a staff Radiation Oncologist.

Dr. Fein has been a member of the American College of Radiology Committee on Marketing/Public Relations and the National Comprehensive Cancer Network Guideline Committee for Sarcoma since 1996. Since 1999, Dr. Fein has been the director of the Tumor Board at University Medical Center at Princeton.

PUBLICATIONS

Fein DA, Mendenhall WM, Parsons JT, Million RR: T1-T2 squamous cell carcinoma of the glottic larynx treated with radiotherapy: A multivariate analysis of variables potentially influencing local control. International Journal of Radiation Oncology, Biology, Physics 25: 605-611, 1993.

Fein DA, Mendenhall WM, Parsons JT, Million RR: Squamous cell carcinoma of the pharyngeal wall treated with external beam irradiation: Impact of fractionation schedule and treatment technique. International Journal of Radiation Oncology, Biology, Physics 26: 751-757, 1993.

Fein DA, Mendenhall WM, Parsons JT, Stringer SP, Cassisi NJ, Million RR: Carcinoma in situ of the glottic larynx: The role of radiotherapy. International Journal of Radiation Oncology, Biology, Physics 27: 379-384, 1993.

Fein DA, Marcus RB, Parsons JT, Mendenhall WM, Million RR: Lhermitte's sign: Incidence and treatment variables influencing risk after irradiation of the cervical spinal cord. International Journal of Radiation Oncology, Biology, Physics 27: 1029-1033, 1993.

Fein DA, Mendenhall NP, Marsh RDW, Bland KI, Copeland EM III, Million RR: Results of multimodality therapy for inflammatory breast cancer: An analysis of clinical and treatment factors affecting outcome. The American Surgeon 60: 220-225, 1994.

Fein DA, Morgan LS, Marcus RB, Mendenhall WM, Sombeck MS, Freeman DE, Million RR: Stage III Ovarian carcinoma: An analysis of treatment results and complications following hyperfractionated abdominopelvic irradiation for salvage. International Journal of Radiation Oncology, Biology, Physics 29: 169-176, 1994

Fein DA, Mendenhall WM, Parsons JT, McCarty PJ, Stringer SP, Million RR, Cassisi NJ: Carcinoma of the oral tongue: A comparison of results and complications of treatment with radiotherapy and/or surgery. Head and Neck 16: 358-365, 1994.

Million RR, Mendenhall WM, Parsons JT, Fein DA, Cassisi NJ, Stringer SP: Comparison of radiation therapy and surgery in the management of T1-T2 vocal cord carcinoma. In Laryngeal Cancer. Smee R and Bridger GP (eds). Elsevier Science B.V., 1994: 303-307

Million RR, Fein DA, Mendenhall WM, Parsons JT: The prognostic factors for local failure after radiotherapy for T1-T2 glottic carcinoma. In Laryngeal Cancer. Smee R and Bridger GP (eds). Elsevier Science B.V., 1994: 407-413.

Fein DA, Corn BW, Lanciano RM, Herbert SH, Hoffman JP, Coia LR: Management of retroperitoneal sarcomas: Does dose escalation impact on locoregional control? International Journal of Radiation Oncology, Biology, Physics 31: 129-134; 1995.

Fein DA, Nichols RC, Lee WR, Mendenhall WM, Parsons JT, Stringer SP, Cassisi NJ, Million RR: T2-T3 carcinoma of the supraglottic larynx: A comparison of surgery and radiotherapy. Radiation Oncology Investigations 2: 237-244; 1995.

McGee KP, Das IJ, Fein DA, Martin EE, Schultheiss TE, Hanks GE: Picture archiving and communications systems in radiation oncology (PACSRO): tools for a physician-based digital image review system. Radiotherapy and Oncology 34:54-62; 1995.

Fein DA, Corn BW, Hanlon AL, Curran WC, Coia LR: Acute parotitis during mantle irradiation: Incidence, onset, duration and treatment. Radiation Oncology Investigations 2:291-294; 1995.

Fein DA, Lee WR, Lanciano RM, Corn BW, Herbert SH, Hanlon AL, Hoffman JP, Eisenberg BL, Coia, LR: Management of extremity soft tissue sarcomas with limb-sparing surgery and postoperative irradiation: Do total dose, overall treatment time and the surgery-radiotherapy interval impact on local control? International Journal of Radiation Oncology, Biology, Physics 32:969-976; 1995.

Fein DA, Lee WR, Hanlon AL, Ridge JA, Curran WJ, Coia LR: Pretreatment hemoglobin level influences local control and survival of T1-T2 squamous cell carcinomas of the glottic larynx. Journal of Clinical Oncology 13:2077-2083; 1995.

Das IJ, McGee KP, Fein DA, Milito SJ, Shammo G, Curran WJ, Coia LR: Use of multi-planar reformatted radiographic and digitally reconstructed radiographic images for planning conformal radiation therapy. Radiographics 15:1483-1488; 1995.

Fein DA, Lee WR, Amos WR, Hinerman RW, Parsons JT, Mendenhall WM, Stringer SP, Cassisi NJ, Million RR: Oropharyngeal carcinoma treated with radiotherapy: A 30 year experience. International Journal of Radiation Oncology, Biology, Physics 34:289-296; 1996.

Nall AV, Brownlee RE, Colvin CP, Schultz G, Fein DA, Cassisi NJ, Nguyen T, Kalra, A: Transforming growth factor beta-1 improves wound healing and random flap survival in normal and irradiated rats. Archives of Otolaryngology Head Neck Surgery 122: 171-177; 1996.

Fein DA, McGee KP, Schultheiss TE, Fowble BL, Hanks GE: Intra-and interfractional reproducibility of tangential breast fields: A prospective on-line portal imaging study. International Journal of Radiation Oncology, Biology, Physics 34:733-740; 1996.

Fein DA, Lee WR, Hanlon AL, Ridge JA, Curran WJ, Coia LR: Do overall treatment time, field size, and treatment energy influence local control of T1-T2 squamous cell carcinomas of the glottic larynx? International Journal of Radiation Oncology, Biology, Physics 34:823-831; 1996.

Fein DA, Fowble BL, Hanlon AL, Hoffman JP, Sigurdson ER, Eisenberg BL: Does the placement of surgical clips within the excision cavity influence local control for patients treated with breast-conserving surgery and irradiation? International Journal of Radiation Oncology, Biology, Physics 34: 1009-1017; 1996.
Corn BW, Hernandez E, Anderson L, Fein DA, Dunton CJ, Heller P: Phase I/II study of concomitant irradiation and carboplatin for locally advanced carcinoma of the uterine cervix: An interim report. American Journal of Clinical Oncology 19:317-321; 1996.

McLaughlin MP, Parsons JT, Fein DA, Stringer SP, Cassisi NJ, Mendenhall WM, Million RR: Salvage surgery after radiotherapy failure in T1-T2 squamous cell carcinoma of the glottic larynx. Head and Neck 18:229-235; 1996.

Fowble B, Fein DA, Hanlon AL, Eisenberg BL, Hoffman JP, Sigurdson ER, Daly MB, Goldstein LJ: The impact of tamoxifen on breast recurrence, cosmesis, complications, and survival in estrogen receptor-positive early-stage breast cancer. International Journal of Radiation Oncology, Biology, Physics 35:669-677; 1996.

Fein DA, Hanlon AL, Corn BW, Curran WJ, Coia LR: The influence of lymphangiography on the development of hypothyroidism in patients irradiated for Hodgkin's disease. International Journal of Radiation Oncology, Biology, Physics 36: 13-18, 1996.

Fein DA, Pinover WH, Corn BW: Radiation therapy's role in the management of ovarian carcinoma. Cancer Care News, Fall 1996.
McGee KP, Fein DA, Hanlon AL, Schultheiss TE, Fowble BL: The value of setup portal films as an estimate of a patient's position throughout fractionated tangential breast irradiation: An on-line study. International Journal of Radiation Oncology, Biology, Physics 37:223-228, 1997.

Fein DA, Hanlon AL, Lee WR, Ridge JA, Coia LR: Neck failure in T2N0 squamous cell carcinoma of the true vocal cords: The Fox Chase experience and review of the literature. American Journal of Clinical Oncology 20(2):154-157, 1997.

Das IJ, Cheng CW, Fein DA, Coia LR, Curran WJ, Fowble B: Dose estimation to critical organs from vertex field treatment of brain tumors. International Journal of Radiation Oncology, Biology, Physics 37:1023-1029; 1997.

Fein DA, Fowble BL, Hanlon AL, Hooks MA, Hoffman JP, Sigurdson ER, Jardines LA, Eisenberg BL: Identification of women with T1-T2 breast cancer at low risk of positive axillary nodes. Journal of Surgical Oncology 65 (1):34-39; 1997.

Das IJ, Cheng CW, Fein DA, Fowble B: Patterns of dose variability in radiation prescription of breast cancer. Radiotherapy and Oncology 44:83-89; 1997.

Das IJ, Lanciano RM, Fein DA, Movsas B, Schultheiss TE: CT-simulation and CT-CT image fusion for reduction of small bowel volume in pelvic irradiation. Accepted for publication to ACQSIM User Conference Journal.

Cheng CW, Das IJ, Tang W., Chang XS Tsai JS, Ceberg C., DeGaspie B, Singh R., Cassady JR, Fein DA, Fowble BL: Dosimetric comparison of treatment planning systems in irradiation of breast with tangential fields. International Journal of Radiation Oncology, Biology, Physics 38:835-842; 1997.

Fowble B, Hanlon AL, Fein DA, Hoffman JP, Sigurdson ER, Patchefsky A, Kessler H: Results of conservative surgery and radiation for mammographically detected ductal carcinoma in situ (DCIS). International Journal of Radiation Oncology, Biology, Physics 38:949-957; 1997.

Freedman GM, Fowble BL, Hanlon AL, Fein DA, Hoffman JP, Sigurdson ER, Goldstein LJ : Postmastectomy radiation and adjuvant systemic therapy: Assessment of clinical, pathologic, and treatment-related factors influencing local-regional control. The Breast Journal 3: 1-8; 1997.

Algan O, Fowble B, McNeeley S, Fein DA: Use of the prone position in radiation treatment for women with early stage breast cancer. International Journal of Radiation Oncology, Biology, Physics 40:1137-1140; 1998.

Lattanzi JP, Fein DA, McNeeley SW, Shaer AH, Movsas B, Hanks GE: CT-MRI image fusion: A clinical evaluation of an innovative approach for improved tumor localization in CNS lesions. Accepted for publication to Radiation Oncology Investigations.

Fein DA, Hanlon AL, Corn BW, Fein DA, Coia LR: Lymphangiography: The positive/negative predictive value and the influence on the rate of hypothyroidism in patients irradiated for Hodgkin's disease. Accepted for publication to British Journal of Radiology.

Siegelmann-Danieli N, Hanlon A, Ridge JA, Padmore R, Fein DA, Langer CJ: Oral tongue cancer in thirty young individuals: Institutional experience and comparison with older patients. Accepted for publication to the Journal of Clinical Oncology.

Fein DA, Lattanzi JP, Ridge JA, McNeeley SW, Shaer AH, Das IJ, Hanks GE: CT-MRI image fusion: An evaluation of an innovative radiographic approach for improved tumor localization in nasopharyngeal tumors. Submitted to Head and Neck.

Movsas B, Fein DA, Hanlon AL, McNeeley S, Hanks G: Is it necessary to irradiate the entire seminal vesicles in patients at risk for seminal vesicle invasion? Submitted for publication to International Journal of Radiation Oncology, Biology, Physics.

Freedman GM, Fowble BL, Hanlon AL, Myint MA, Hoffman JP, Sigurdson ER, Eisenberg B, Goldstein LJ, Fein DA: A close or positive margin after mastectomy is not an indication for chest wall irradiation except in women aged fifty or younger. Submitted for publication to International Journal of Radiation Oncology, Biology, Physics.

Freedman GM, Fowble B, Hanlon A, Fein DA, Nicolaou N, Hoffman J, Sigurdson E, Boraas M, Goldstein L: Patients with close or positive margins treated with conservative surgery and radiation have an increased risk of recurrence that is delayed by adjuvant systemic therapy. Submitted for publication to International Journal of Radiation Oncology, Biology, Physics.

Hooks M, Eisenberg B, Sigurdson E, Hoffman J, Hanlon A, Fein DA, Fowble B: Mammographically detected breast cancer: Resection margin status at needle localization biopsy and implications for reexcision. In preparation.