Robert M. Cardinale, M.D.

After completing an undergraduate degree with high honors, Robert M. Cardinale received his Medical Degree from the University of Maryland School of Medicine in 1991. He completed his residency in Radiation Oncology at Johns Hopkins Hospital in 1994 and was appointed Chief Resident in Radiation Oncology at Johns Hopkins Hospital in 1995.

Dr. Cardinale was certified by the American Board of Radiology in Radiation Oncology in 1996. He has served in several academic positions, including Laboratory Investigator at The Johns Hopkins Oncology Center in 1994, Associate Professor for the Department of Radiation Oncology, and Clinical Director of the Department of Radiation Oncology at the Medical College of Virginia.

He is a member of several professional organizations, including the Society for Neuro-Oncology, The American Board of Radiology and the American College of Radiation Oncology. His administrative experience includes several committee positions, including University Senator (alternate), and American Board of Radiology Written Examination Task Force.

Dr. Cardinale is a nationally recognized leader in the fields of Radiation Oncology and Sterotactic Radiosurgery. His special awards and honors are numerous and include the Resident Teaching Award from the Department of Radiation Oncology. Dr. Cardinale was elected as a “Best Physician” by Richmond Magazine, and received the Civilian Award from the University of Maryland School of Medicine. He has written numerous publications in radiation oncology, including several book chapters, editorials, and abstracts, and has presented his work at over fifty national and international scientific meetings.

Dr. Cardinale joined the Radiation Oncology staff at Princeton Radiology in 2001, and is a Radiation Oncologist at the Princeton Radiology Pharmaceutical Research Center in Princeton. He continues as an active investigator with the Radiation Therapy Oncology Group.


Kavanagh BD, Wu Q, Cardinale RM, et al: Clinical application of intensity-modulated radiotherapy (IMRT) for cervix cancer. In press, Computer Aided Surgery, 2000.

Manning MA, Cardinale RM, Schmidt-Ullrich RK, et al: Extracorporeal irradiation of tumorous calvarium. In press, J. Neurosurgery, 2000.

Benedict SH, Cardinale RM, Wu Q, Zwicker RD, Broaddus WC, Mohan R: Intensity modulated stereotactic radiosurgery using dynamic micro-multileaf collimation. In press, Int. J. Radiat. Oncol. Biol. Phys., 2000.

Benedict SH, Cardinale RM, Zwicker RD, Kavanagh BD, Bump EA, Solberg TD, Boone RA, Mohan R: Application of a photogrammetry-based patient positioning and monitoring system for extracranial stereotactic radiotherapy, In press, Int. J. Radiat. Oncol. Biol. Phys., 2000.

Kavanagh BD, Sagreti EM, Koo DT, Amir C, Arthur DW, Wheelock J, Cardinale RM, Schmidt-Ullrich RK, Longterm local control and survival following concomitant boost accelerated radiotherapy for locally advanced cervix cancer. In press, Amer. J. Clin. Oncol., 2000.

Manning MA, Cardinal RM, Broaddus WC, et al: Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of brain metastases. Int. J. Radiat. Oncol. Biol. Phys. 47(3): 603-8, 2000.

Kavanagh BD, Campbell RL, Patterson JW, O’Neill RL, Cardinale RM, Kaugars GB: Desmoplastic melanoma of the palatal alveolar mucosa: sustained disease-free survivorship after surgery and post-operative radiotherapy. Oral Surg., Med. And Path, 89: 465-70, 2000.

Kavanagh BD, Cardinale RM et al: Digital fluoroscopy for placement verification and treatment planning in gynecological brachytherapy. Radiology, 215(3); 900-903, 2000.

Cardinale RM, Wu Q, Benedict SH, Bump E, Kavanagh BD, Mohan R: determining the optimal block margin on the planning target volume for extracranial stereotactic radiotherapy. Int. J. Radiat. Oncol. Biol. Phys., 45(2): 515-520, 1999.

Kavanagh BD, Cardinale RM, Kachnic LA: MCV: Management of malignant glioma. Oncology, 12 (11): 1669-1673, 1998.
Cardinale RM: High dose small field re-irradiation of brain tumors using a modified radiosurgical technique. J. Radiosurgery, 1(4): 281, 1998.

Cardinal RM, Benedict S, Zwicker R, Gaballa HA, Wu Q, Mohan R: A Comparison of three stereotactic radiotherapy techniques, arcs, vs noncoplanar fixed beams vs intensity modulation. Int. J. Radiat. Oncol. Biol. Phys., 42(2): 431-436, 1998.

Cardinale RM, Schmidt-Ullrichl R, Benedict S, Zwicker RD, Broaddus W: An accelerated radiotherapy regimen for malignant gliomas using stereotactic concomitant boosts for dose escalation. Radi. Oncol. Investig. Vol 6(4): 175-181, 1998.

Cardinale RM, Dillahay L., Williams J. Tabassi K., Brem H, Lee DJ: Effect of Tirapazamine given by systemic injection or intratumoral polymer on the radiosensitivity of human glioblastoma multiforme in vivo. Radiat. Oncol. Investig. 6(2): 63-70, 1998.

Abrams, RA, Cardinale RM, Enger C, Haulk TL, Osterman F, Sitzman JV: Influence of prognostic groupings and treatment outcomes in the management of unresectable hepatoma: Int. J. Rad. Oncol. Biol. Phys. 39(5): 1077-1085, 1997.

Cardinale RM: US Patent of Invention, Method of cancer tumor treatment by slow release delivery of 1,2,4-benzotriazine oxides to tumor site. United States Patent and Trademark Office Press, Patent number 5637085, 1997.